First, if the benzene was released into the air, get fresh air by leaving the area where the benzene was released. Moving to an area with fresh air is a good way to reduce the possibility of death from exposure to benzene in the air.

If the benzene release was outside, move away from the area where the benzene was released. If the benzene release was indoors, get out of the building as quickly as possible. If you are near a release of benzene, emergency coordinators may tell you to either evacuate the area or to “shelter in place” inside a building to avoid being exposed to the highly toxic chemical.

If your eyes are burning or your vision is blurred, rinse your eyes with plain water for 10 to 15 minutes. If you wear contacts, remove them after washing your hands and put them with the contaminated clothing. Do not put the contacts back in your eyes (even if they are not disposable contacts). If you wear eyeglasses, wash them with soap and water. You can put your eyeglasses back on after you have thoroughly washed them.
 
After you have washed yourself, place your clothing inside a plastic bag. Try your best to avoid touching any contaminated areas of the clothing. If you can't avoid touching contaminated areas, or you aren't sure where the contaminated areas are, wear rubber gloves or put the clothing in the bag using tongs, tool handles, sticks, or similar objects. Anything that touches the contaminated clothing should also be placed in the bag. Seal the bag, and then seal that bag inside another plastic bag. Disposing of your clothing in this way will help protect you and other people from any chemicals that might be on your clothes. When the local or state health department or emergency personnel arrive, tell them what you did with your clothes. The health department or emergency personnel will arrange for further disposal. Do not handle the plastic bags yourself.
 
If you think your water supply may have benzene in it, drink bottled water until you are sure your water supply is safe. If someone has swallowed benzene, do not try to make them vomit or give them fluids to drink. Also, if you are sure the person has swallowed benzene, do not attempt CPR. Performing CPR on someone who has swallowed benzene may cause them to vomit. The vomit could be sucked into their lungs and damage their lungs. Seek medical attention right away. Dial 911 and explain what has happened.

Benzene poisoning is treated with supportive medical care in a hospital setting. No specific antidote exists for benzene poisoning; however, patients who seek immediate medical attention have the greatest chance of recovery.